The combination of adipose-derived Schwann-like cells and acellular nerve allografts promotes sciatic nerve regeneration and repair through the JAK2/STAT3 …
X Fu, Y Wang, W Fu, D Liu, C Zhang, Q Wang, X Tong - Neuroscience, 2019 - Elsevier
Schwann cells (SCs) combined with acellular nerve allografts (ANAs) effectively promote the
regeneration and repair of peripheral nerves, but the exact mechanism has not been fully
elucidated. However, the disadvantages of SCs include their limited source and slow rate of
expansion in vitro. Previous studies have found that adipose-derived stem cells have the
ability to differentiate into Schwann-like cells. Therefore, we speculated that Schwann-like
cells combined with ANAs could profoundly facilitate nerve regeneration and repair. The aim …
regeneration and repair of peripheral nerves, but the exact mechanism has not been fully
elucidated. However, the disadvantages of SCs include their limited source and slow rate of
expansion in vitro. Previous studies have found that adipose-derived stem cells have the
ability to differentiate into Schwann-like cells. Therefore, we speculated that Schwann-like
cells combined with ANAs could profoundly facilitate nerve regeneration and repair. The aim …
